Renal diabetes insipidus

Reasons
Diagnosis
Diet and nutrition
In children
Symptoms
Treatment
Renal
Central
Medications
Complications
Tests
Disability

 

renal diabetes insipidusInsipidus renal diabetes (nephrogenic diabetes) in most cases is a hereditary disease. It occurs when the disturbance in the renal sensitivity to vasopressin, the amount of which in the blood is within normal limits. Kidney with diabetes insipidus excrete urine with a low specific weight is mostly water with a reduced amount of salts and other substances.

Vasopressin (aka antidiuretic hormone) regulates the body's water balance and osmotic composition of all kinds of liquids of an organism for its normal functioning. Under the influence of vasopressin is regulated by the reverse absorption of water in kidneys, regulates the amount of urine. Violation of osmotic equilibrium and extracellular fluid the liquid portion of blood can cause death.

the antidiuretic hormone (vasopressin) lower blood pressure, reduced body temperature, beta-blockers, the drugs haloperidol, clonidine and carbamazepine and alcohol.

the Main causes of renal diabetes insipidus is a genetic disease of Central nervous system sarcoidosis, vascular disorders, aneurysms of cerebral vessels. The cause of the disease can be metastatic and malignant tumors, meningitis and encephalitis, infectious and autoimmune diseases, syphilis and craniopharyngeoma.

it's Not uncommon renal diabetes insipidus occurs after injuries of the skull or brain, surgery on the brain. The disease occurs in men and women with equal frequency.

Early signs of the disease are increase in urine volume (5-6 liters in a day) and increased thirst. As a result, the patient drinks equal amount of fluid as a result of the night urination, insomnia and fatigue. With the progression of the disease the amount of urine may increase to 20 liters per day.

a Painful condition accompanied by headache, dryness of the skin, weight loss, reduction of salivation. To these symptoms are joined by a rapid heart rate and lowering blood pressure. In children under 1 year painful condition can be severe - neurological disorders, causeless vomiting, sharp increase in body temperature. The older children can suffer from incontinence of urine (enuresis).

In the treatment of renal diabetes insipidus used a synthetic analogue of vasopressin is desmopressin or adiuretin DM, which is administered through the nose (intranasally) twice a day. In some cases, use of pitressin Tanat - the drug is long-acting (once in 3-5 days). Recommended diet with plenty of carbs for frequent meals.