Nephropathy in diabetes mellitus, nephrogenic diabetes

Renal failure


nephropathy in diabetes mellitusPathological processes that occur in kidney, can be a complication of diabetes. But do not forget about the existence of diabetes insipidus, in which the same pathological process in the big role to influence on the renal tissue. The symptoms and the essence of the process in these diseases are of a fundamentally different nature.


Nephropathy in diabetes mellitus

Diabetic nephropathy is a bilateral pathological process, which leads to a sharp decrease in the function of both kidneys. It is the most serious complication of diabetes.

the Occurrence of nephropathy in diabetes is due to several factors. One of them - current long-term hyperglycemia, in which there are various metabolic disorders. High level of glycated protein, the toxic effect of high glucose levels, destructive disorders in the capillaries, caused by biochemical disorders, hyperlipidemia - all these factors adversely affect the tissues of the kidneys. The next factor is the violation of intrarenal blood flow. Also to the development of diabetic nephropathy predispose genetic features.

nephropathy of diabetes there is a violation of the filtration capacity of the kidneys in which they start to miss a squirrel, withdrawing from the body with urine. The process is generally very slow and does not manifest itself clinically. In time a person may experience the swelling of the body due to the loss of protein and high blood pressure. In the later stages of the disease, in connection with sharp deterioration of the barrier function of the kidneys in the blood there is a high level of creatinine, indicating a toxemia.


Nephrogenic diabetes

nephrogenic diabetesUnder nephrogenic diabetes commonly understood as disease in which there is a sharp decrease in the ability of the kidneys to concentrate the filtrate that enters the nephron, whereby there is excessive loss of body fluid. The inability of nephrons to perform the reverse absorption of water occurs due to the lack of response of receptors to the action of the hormone antidiureticheskogo.

Nephrogenic diabetes insipidus is a disease that mainly occurs in men. Against the background of excess fluid the patient reports a constant feeling of thirst, which may be the only symptom of the disease. Process excessive secretion of urine may lead to severe dehydration that may cause death.